According to a source within the restaurant industry, Uno Pizzeria and Grill in Waltham is no longer in business, with a tweet from @EyesOnWaltham seeming to confirm this today as well. This is the second Uno location to close of late, as the outlet in Cambridge's Harvard Square shuttered this past September; it looks like locations in Boston (3), Braintree, Burlington, Dedham, Framingham, Revere, Swampscott, and Woburn remain in operation.
Uno was established in Chicago in 1943, with Uno Restaurant Holdings now having its headquarters in West Roxbury.
The address for this now-closed restaurant in Waltham was: Uno Pizzeria and Grill, 155 Bear Hill Road, Waltham, MA, 02451. The website for all locations can be found at https://www.unos.com/>
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[Related article from our sister site (Boston's Hidden Restaurants): Slideshow--Twelve Pizzas in the Boston Area and Beyond]